The low carbon development, industrial structural optimization and upgrade of JJJ as a national key strategy region plays a key role in China's low carbon industrial development, carbon emission reduction performance of sectors is of significance for regional carbon emission reduction. Dynamic panel GMM model and VAR model are used to analyze the impacts of JJJ industrial structural rationalization and optimization on carbon emission, and multiple-formula-linked regression is applied to logical causality and short-term shock effects of related economy variables. Results show carbon emission can be reduced upon JJJ industrial structural optimization and rationalization, although varying with localities. This paper offers suggestions on carbon emission reduction according to the impacts of JJJ industrial structural optimization on carbon emission.